Pathogenesis of Intradialytic Hemodynamic Instability
Annotatsiya
Ma'lumot: tadqiqot intradialitik gemodinamik beqarorlik mexanizmlarini o'rganadi, bu gemodializdan o'tayotgan surunkali buyrak kasalligi bilan og'rigan bemorlarni boshqarishda muhim muammo bo'lib qolmoqda. Ushbu holatga yordam beradigan omillarni tushunish bemorning natijalarini yaxshilash uchun juda muhimdir.
Maqsad: intradialitik gemodinamik beqarorlikka olib keladigan birlamchi patofiziologik mexanizmlarni ko'rib chiqish va tahlil qilish.
Materiallar va usullar: sharh gemodializ paytida gemodinamik o'zgarishlarga qaratilgan so'nggi tadqiqotlar va klinik tadqiqotlar ma'lumotlarini sintez qiladi. Tahlil plazma hajmini kamaytirish, miokard kontraktilligi va tizimli perfuziya kabi omillarni o'z ichiga oladi.
Natijalar: intradialitik gemodinamik beqarorlikning asosiy mexanizmlari plazma hajmining pasayishi, venoz qaytishning pasayishi, pastki chap qorincha oldindan yuklanishi va kontraktilligi, insult va daqiqali hajmlarning pasayishini o'z ichiga oladi. Ikkilamchi omillarga xronotropik etishmovchilik, patologik miokardni qayta qurish va qorin, miya va koronar qon aylanishiga ta'sir qiluvchi tizimli va mintaqaviy perfuziya etishmovchiligi kiradi.
Xulosa: intradialitik gemodinamik beqarorlik patogenezini har tomonlama tushunish yurak-qon tomir xavfini kamaytirish va bemorning hayot sifatini yaxshilash uchun maqsadli terapevtik aralashuvlarning muhimligini ta'kidlaydi.
Mualliflar haqida
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