Surgical treatment of post-infarction ventricular septal defect and left ventricular aneurysm

https://doi.org/10.70626/cardiouz-2025-2-00038
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Abstract

The article focuses on the possibilities of modern surgical interventions for conditions including post-infarction ventricular septal rupture (PIVSR) repair, left ventricular reconstruction, and coronary artery bypass grafting.


Current clinical case highlights the relevance of mechanical complications of acute myocardial infarction, which, despite advances in cardiology and cardiac surgery, are still associated with high mortality. The development and standardization of surgical correction methods for these conditions, including optimal timing of surgery, remain important areas for improving treatment outcomes in patients with severe forms of myocardial infarction.


The described clinical case illustrates the complexity and multi-stage process of treating patients with PIVSR, from diagnosis to the postoperative period.


Data on the clinical condition, instrumental and laboratory research methods (echocardiography, coronary ventriculography), a detailed description of the performed surgical procedure, and the results of surgical intervention are presented, which can serve as a valuable guide for clinicians encountering similar cases in their practice.


The need for continued accumulation of clinical material and research in this area is indicated in order to optimize the results of surgical treatment for patients in this severe category.

About the Authors

List of references

Arnaoutakis GJ, Zhao Y, George TJ, Sciortino CM, McCarthy PM, Conte JV. Surgical repair of ventricular septal defect after myocardial infarction: outcomes from the Society of Thoracic Surgeons National Database. Ann Thorac Surg. 2012;94:436– 444.

Moreyra AE, Huang MS, Wilson AC, Deng Y, Cosgrove NM, Kostis JB. Trends in incidence and mortality rates of ventricular septal rupture during acute myocardial infarction. Am J Cardiol. 2010; 106:1095–1100.

Topaz, O., Mallon, S. M., Chanine, R. A., Sequeira, R. F., Myerburg, R. J. Acute ventricular septal rupture.

Angiographicmorphologic features and clinical assessment. Chest 1989, 95(2): 292–298

Radford MJ, Johnson RA, Daggett WM Jr, Fallon JT, Buckley MJ, Gold HK, Leinbach RC Ventricular septal rupture: a review of clinical and physiologic features and an analysis of survival. Circulation. 1981 Sep;64(3):545-553.

Crenshaw B.S., Granger C.B., Birnbaum Y., Pieper K.S., Morris D.C., Kleiman N.S., Vahanian A., Califf, R.M., Topo E.J. Risk factors, angiographic patterns, and outcomes in patients with ventricular septal defect complicating acute myocardial infarction. GUSTO-I (Global Utilizationof Streptokinase and TPA for Occluded Coronary Arteries) Trial Investigators. Circulation 2000, 101(1): 27–32.

Yip HK, Fang CY, Tsai KTet al . The potential impact of primary percutaneous coronary intervention on ventricular septal rupture complicating acute myocardial infarction. Chest 2004; 125: 1622–1628.

Latham PM, Lectures on subjects connected with clinical medicine comprising disease of the heart.

London: Longmans, Brown, Green and Longmans II 1846: 168-176

Menon V, Webb J.G, Hillis L.D; SHOCK Investigators Outcome and profile of ventricular septal rupture with cardiogenic shock after myocardial infarction. a report from the SHOCK Trial Registry. J Am Coll Cardiol. 36 2000:1110-1116.

Skehan JD, Carey C, Norrell MS, de Belder M, Balcon R, Mills PG. Patterns of coronary artery disease in postinfarction ventricular septal rupture. Br Heart J 1989; 62: 268-272

Dellborg M., Held P., Swedberg K.: Rupture of the myocardium. Occurrence and risk factors. // Br. Heart

J. 1985. - Vol. 54; 11

Braunwald E., Zipes D.P., Libby P. Heart Disease: A Textbook of Cardiovascular Medicine. – Philadelphia: Saunders, 2019. – 2028 p.

Topol E.J., Teirstein P.S. Textbook of Interventional Cardiology. – 7-е изд. – Elsevier, 2020. – 1176 p.

Nakatani S. Percutaneous and Surgical Treatment of Post-Myocardial Infarction Ventricular Septal Rupture. – Journal of Cardiology, 2017. – Vol. 70(2). – P. 93–102.

Adams J.E., Abendschein D.R., Jaffe A.S. Biochemical markers of myocardial injury. – Circulation, 2020. – Vol. 122(24). – P. 2728–2735.

Birnbaum Y., Fishbein M.C. Ventricular Septal Rupture After Acute Myocardial Infarction. – Circulation, 2018. – Vol. 138(12). – P. 159–168.

Buckberg G.D., Athanasuleas C.L. Surgical Ventricular Restoration for Ischemic Cardiomyopathy. – Progress in Cardiovascular Diseases, 2019. – Vol. 42(2). – P. 131–138.

Khaitan L., Sutter F.P. Management of Mechanical Complications of Myocardial Infarction. – Seminars in Thoracic and Cardiovascular Surgery, 2020. – Vol. 12(1). – P. 56–67.

Lundblad R., Abdelnoor M., Svennevig J.L. Outcome after surgery for ventricular septal rupture following acute myocardial infarction. – Scandinavian Cardiovascular Journal, 2018. – Vol. 52(4). – P. 243–250.

Menon V., Webb J.G., Hillis L.D. The Role of Echocardiography in the Diagnosis of Post-Myocardial Infarction Complications. – American Journal of Cardiology, 2017. – Vol. 108(5). – P. 1201–1210.

Antman E.M., Loscalzo J. Acute Coronary Syndromes. – New England Journal of Medicine, 2019. – Vol. 380(10). – P. 234–245.

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How to Cite

Surgical treatment of post-infarction ventricular septal defect and left ventricular aneurysm. (2025). CARDIOLOGY OF UZBEKISTAN, 2(1), 58-70. https://doi.org/10.70626/cardiouz-2025-2-00038

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