Vol. 2 No. 2 (2025): April - June
145-151
2025-06-30
Open Access

Systematic Review of Valve Surgery with Continuous Coronary Perfusion on Beating Heart in Patients with Low Left Ventricular Ejection Fraction.

orcidUmid T.Khayrullaev
orcidGuzal U.Mullabaeva
orcidIslamjan M.Sharipov
DOI: https://doi.org/10.70626/cardiouz-2025-2-00046

Received: 2025-04-01 10:53:58

Published: 2025-06-30

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Abstract

Aim. Beating-heart continuous coronary perfusion (BHCCP) is an alternative to cardioplegic arrest in valve surgery, potentially reducing ischemic reperfusion injury, especially in high-risk patients with low left ventricular ejection fraction (LVEF).


Materials and methods. A systematic review of prospective and observational studies was conducted, focusing on BHCCP versus cardioplegia in valve surgery, with emphasis on patients with LVEF <35%.


Results. Studies (e.g., Matsumoto et al., 2002) showed no significant difference in mortality or major complications, but BHCCP reduced myocardial damage markers (e.g., Troponin I, CK-MB) by 20–40% compared to cardioplegia. Clinical outcomes remained comparable across groups.


Conclusion. BHCCP is a safe alternative to cardioplegia, with potential benefits in myocardial protection, though high-quality randomized trials are needed to confirm clinical superiority.

Keywords

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About the Authors

Umid T.Khayrullaev
umid.0911@mail.ru
Republican Specialized Scientific and Practical Medical Center of Cardiology
Guzal U.Mullabaeva
guzal-m@inbox.ru
Republican Specialized Scientific and Practical Medical Center of Cardiology
Islamjan M.Sharipov
islamsharipov@mail.ru
Republican Specialized Scientific and Practical Medical Center of Cardiology

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Copyright (c) 2025 У.Т. Хайруллаев , Г.У. Муллабаева , И.М. Шарипов (Автор)

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This work is licensed under a Creative Commons Attribution 4.0 International License.

How to Cite

Systematic Review of Valve Surgery with Continuous Coronary Perfusion on Beating Heart in Patients with Low Left Ventricular Ejection Fraction. (2025). CARDIOLOGY OF UZBEKISTAN, 2(2), 145-151. https://doi.org/10.70626/cardiouz-2025-2-00046
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