O'zbekiston Respublikasida karotid havzasi aterosklerozi bilan og'rigan bemorlarda yurak-qon tomir xavfining epidemiologiyasi va baholash: kross-seksion populyatsion tadqiqot
Annotatsiya
Maqsad. Uyqu arteriyasi havzasining aterosklerozi ishemik insultning asosiy patogenetik omillaridan biridir. Mahalliy epidemiologik ma’lumotlarning yetishmasligi sharoitida O‘zbekiston Respublikasida shikastlanishlar tarqalishi va ular bilan bog‘liq xavf omillarini o‘rganish alohida ahamiyatga ega. Tadqiqotning maqsadi – O‘zbekiston kattalar aholisi orasida uyqu arteriyalarining aterosklerotik shikastlanishlari tarqalishini baholash, ular bilan bog‘liq xavf omillarini aniqlash va jins, yosh hamda hududiy xususiyatlarni hisobga olgan holda SCORE shkalasi bo‘yicha yurak-qon tomir xavfini stratifikatsiya qilishdan iborat edi.
Materiallar va usullar. Tahlil Respublika ixtisoslashtirilgan kardiologiya ilmiy-amaliy tibbiyot markazida (Toshkent) o‘tkazilgan aholiga asoslangan kesim tadqiqotiga asoslandi. Umumiy hisobda uyqu arteriyalarining ultratovushli dupleks skanerlovidan o‘tgan 6 425 nafar kattalar bemorlarning ma’lumotlari o‘rganildi. Demografik ko‘rsatkichlar, qon bosimi darajasi, lipid profili, chekish holati, arterial gipertenziya (AG) mavjudligi va SCORE shkalasi bo‘yicha 10 yillik yurak-qon tomir xavfi baholandi. Statistik tahlilda bir omilli va ko‘p omilli logistika regressiya modellari qo‘llanildi.
Natijalar. Uyqu arteriyalarining aterosklerotik o‘zgarishlari 50 yoshdan oshgan erkaklarda sezilarli darajada ko‘proq aniqlangan (p<0,05). Eng kuchli korrelyatsiya arterial gipertenziya bilan kuzatilgan (r=0,85; p<0,001). Chekish va sistolik qon bosimining yuqoriligi blyashka mavjudligi bilan o‘rtacha bog‘liqlikka ega bo‘lgan (p<0,01). Ayrim hududlarda (Samarqand va Navoiy viloyatlari) SCORE o‘rtacha ko‘rsatkichlari yuqori darajaga yetgan.
Xulosa. Ushbu natijalar yuqori xavf guruhlarida arterial gipertenziya nazoratini kuchaytirish va chekish tarqalishini kamaytirishga qaratilgan maqsadli profilaktik dasturlarni joriy etish zarurligini ta’kidlaydi.
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Copyright (c) 2025 Ф.М. Бекметова , Х.Г. Фозилов , С.Я. Абдуллаева , М.Н. Хотамова , А.Ш. Алманова , Ш.Н. Дониёров (Автор)
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