Miokard infarti o‘tkazgan bemorlarda stentlash orqali o‘tkazilgan revaskulyarizatsiyaning chap qorincha otish fraksiyasiga ta‘siri
Annotatsiya
Maqsad. Chap qorincha otish fraksiyasi saqlangan (CHQOF) yoki biroz pasaygan, anamnezida miokard infarkti (MI) o‘tkazgan bemorlarda to‘liq yoki noto‘liq revaskulyarizatsiyaning yurak sistolik funksiyasiga 1 yillik dinamik ta’sirini baholashdan iborat.
Materiallar va usullar. Tadqiqotga anamnezida MI o‘tkazgan 270 nafar bemor jalb qilinib, transtorakal exokardiografiya, klinik tekshiruv xulosalari asosida koronaroangiografiya amaliyoti (KAG) o‘tkazildi. Bemorlarda aterosklerotik koronar tomirlar shikastlanish soniga nisbatan stentlash amaliyoti o‘tkazilishiga qarab 3 guruhga ajratildi: To‘liq revaskulyarizatsiya (TR) (n=115), Noto‘liq revaskulyarizatsiya (NTR) (n=94), Revaskulyarizatsiya bo‘lmagan (RB) guruhi (n=61). Amaliyotdan so‘ng bemorlar standart davolanish bilan uyga chiqarildi. Dinamikada 1 yildan so‘ng bemorlar takroriy EXOKG tekshiruvi orqali CHQOF baholandi.
Natijalar. Dinamikada TR o‘tkazilgan bemorlar guruhida CHQOF 54.0 [47.0; 59.7] dan 55,7 [46,9;61,4] ga statistic ishonarli tarzda ortdi (p = 0,017). NTR bemorlar guruhida CHQOF 53,9 [43,7;56,4] dan 55,7 [46,9;61,4] ga ortsada, ammo natijalar statistik ishonarsiz (p = 0,458). RB bemorlar guruhida CHQOF 50,7 [45; 56,3] dan 48,2 [41,8; 54,3] ga pasaygan(p = 0,011). Chap qorinchani diastolik funktsiyasini baholovchi parametrlar bo‘yicha esa guruhlar orasida statistik ahamiyatga ega farqlar aniqlanmadi.
Xulosa. Infarktdan keyingi davridagi bemorlarda stentlash orqali amalga oshirilgan shikastlangan koronar tomirlar to‘liq anatomik revaskulyarizatsiyasi ChQOF ko‘rsatkichlari sezilarli ijobiy yaxshilanishiga ta’sir etishi aniqlandi.
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Copyright (c) 2025 Э.Я. Турсунов, Р.Д. Курбанов, Н.У. Закиров (Автор)
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