Jild 3 № 2 (2026): Aprel - Iyun
73-82
2026-06-29
Ochiq kirish

Kalsifikatsiyalangan va murakkab koronar zararlanishlarni endovaskulyar davolashda innovatsion texnologiyalar va LMCA revaskulyarizatsiya strategiyalari: sistematik adabiyotlar sharhi

Baxtiyor A.Yuldashov
Xurshid G.Fozilov
Baxtiyor R.Atamuratov
https://doi.org/10.70626/cardiouz-2026-3-00089

Qabul qilingan: 2026-02-22

Nashr etilgan: 2026-06-29

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Annotatsiya

Ushbu sistematik adabiyotlar sharhida kalsifikatsiyalangan va murakkab koronar zarar­lanishlarni endovaskulyar davolashda innovatsion texnologiyalar (tomir ichi litotripsiya, rotatsion va orbital aterektomiya, dori qoplamali ballonlar) hamda chap asosiy koronar arteriya (LMCA) revaskul­yarizatsiya strategiyalari (TOKA va AKSh qiyosiy tahlili) baholangan. Maqsad. Kalsifikatsiyalangan va murakkab koronar zararlanishlarni endovaskulyar davolashda innovatsion texnologiyalarning samaradorligi va xavfsizligini, shuningdek LMCA kasalligida TOKA va AKSh amaliyotlarining qiyosiy natijalarini sistematik ravishda baholash. Materiallar va usullar. 2006–2025 yillarda PubMed, Scopus, Web of Science va Google Scholar ma’lumotlar bazalarida chop etilgan 80 ta ilmiy manba, jumladan Disrupt CAD I–IV, ROTAXUS, PREPARE-CALC, ORBIT I–II, BASKET-SMALL 2, PICCOLETO II, AGENT IDE, SYNTAX, EXCEL, NOBLE, PRECOMBAT kabi yirik randomizatsiyalashtirilgan klinik tadqiqotlar, meta-tahlillar va xalqaro konsensus hujjatlari tahlil qilingan. Natijalar. Tomir ichi litotripsiyasi (IVL) kalsifikatsiyalangan koronar stenozlarda >90% texnik muvaffaqiyat va past asoratlar darajasini ta’minlagan. LMCA kasalligida SYNTAX bali ≤22 bo’lgan bemorlarda TOKA va AKSh natijalari o’xshash; SYNTAX bali ≥33 bo’lganda AKSh ustunligi aniqlangan. IPD meta-tahlilga ko’ra, spontan MI xavfi TOKA guruhida 2,35 barobar yuqori (p<0,0001). DCB kichik tomirlar kasalligida DES ga non-inferior ekanligi tasdiqlangan. Xulosa. Innovatsion kalsifikatsiya modifikatsiya texnologiyalari murakkab koronar zararlanishlarni davolash imkoniyatlarini sezilarli kengaytirgan. LMCA kasalligida revaskulyarizatsiya usulini tanlashda SYN-TAX bali, qandli diabet holati va Kardiologik konsilium yondashuvi hal qiluvchi ahamiyat kasb etadi.

Kalit so‘zlar

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Mualliflar haqida

Baxtiyor A.Yuldashov
ybaxtiyorjon@gmail.com
Respublika ixtisoslashtirilgan kardiologiya ilmiy-amaliy tibbiyot markazi
Xurshid G.Fozilov
hurshidfozilov1976@icloud.com
Respublika ixtisoslashtirilgan kardiologiya ilmiy-amaliy tibbiyot markazi
Baxtiyor R.Atamuratov
baxtiyor-cardio@mail.ru
Respublika ixtisoslashtirilgan Kardiologiya ilmiy-amaliy tibbiyot markazi

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Qanday iqtibos keltirish kerak

Kalsifikatsiyalangan va murakkab koronar zararlanishlarni endovaskulyar davolashda innovatsion texnologiyalar va LMCA revaskulyarizatsiya strategiyalari: sistematik adabiyotlar sharhi (B. Yuldashov, X. Fozilov, & B. Atamuratov, Trans.). (2026). O’ZBEKISTON KARDIOLOGIYASI, 3(2), 73-82. https://doi.org/10.70626/cardiouz-2026-3-00089
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