Гендерные особенности дилатационной кардиомиопатии в узбекской популяции

Dilated kardiyomiyopatiya (DKMP) — bu miyokardning eng tarqalgan ishemiya bo‘lmagan kasalliklaridan biri bo‘lib, u sistolik disfunktsiya va yurak bo‘shliqlarining dilatasiyasi bilan tavsiflanadi. DKMP ning genderga xos oqimi va prognozi hali yetarlicha o‘rganilmagan.
Maqsad. O‘zbekistondagi aholi orasida DKMP bilan kasallangan bemorlarning anamnezi, klinikasi va funksional parametrlari bo‘yicha genderga xos xususiyatlarni baholash.
Materiallar va metodlar. 2010–2017 yillarda RSNPMK kardiologiyasi bo‘limida davolangan 269 nafar DKMP bemorining (180 erkak, 89 ayol) ma'lumotlari retrospektiv tahlil qilindi. Debyut yoshi, kasallik davomiyligi, shifoxonaga yotqizish, NYHA sinfi, gemodinamika va olti daqiqalik yurish testi baholandi. Statistikaning tahlili — Studentning t-kriteryasi, χ2, p< 0.05.
Natijalar. Ayollar kasallik tashxisi qo‘yilganida erkaklarga nisbatan yoshroq bo‘lgan (33,7 ga qarshi 41,3 yosh; p < 0.001), ular kasallik tarixiga qisqaroq ega (p = 0.041) va ko‘proq shifoxonaga yotqizilgan (75% ga qarshi 65%; p = 0.041). NYHA, qon bosimi va nafas olishda sezilarli farqlar aniqlanmadi. Erkaklar jismoniy chidamlilikda yaxshiroq natijalar ko‘rsatdi (p = 0.191).
Xulosa. Muhim gender farqlari aniqlangan bo‘lib, bu DKMP bemorlarini davolashda shaxsiylashtirilgan yondashuv zarurligini tasdiqlaydi.

Kalit so‘zlar

Adabiyotlar ro'yxati

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