Keksalardagi COVID-19 kasalligining o’ziga xos xususiyatlari
Annotatsiya
Dolzarbligi. COVID-19 pandemiyasi, ayniqsa, keksalar uchun jiddiy sog’liq xavflarini keltirib chiqardi. Ushbu yosh guruhida COVID-19ning ta’siri bo’yicha o’tkazilgan tadqiqotlar turli xil atypik klinik belgilarni, asoratlar va tashxislash va davolashdagi qiyinchiliklarni ta’kidladi. Ushbu maqolaning maqsadi — keksalarda COVID-19ning o’ziga xos xususiyatlarini o’rganish va samarali tashxislash va davolash usullarini taklif qilishdir.
Materiallar va metodlar. Ushbu maqolada 60 yoshdan katta 4965 keksadan iborat 20 ta klinik tadqiqotdan olingan ma’lumotlar tahlil qilingan. Tadqiqotlar keksalarda COVID-19 bilan bog’liq klinik simptomlar, laboratoriya natijalari va asoratlarni baholaydi. Turli diagnostik vositalar, jumladan, polimeraza zanjir reaktsiyasi (PZR) testi va tasvirlash texnikalari, shuningdek, ushbu holatlarda qo’llanilgan davolash rejalari ko’rib chiqilgan.
Natijalar. Natijalar shuni ko’rsatdiki, keksalar odatda kognitiv disfunktsiya, zaiflik va g’ayrioddiy oshqozon-ichak simptomlari kabi atypik klinik belgilarni ko’rsatishadi. Laboratoriya natijalari ko’pincha limfotsitopeniya, D-dimer darajalarining oshishi va C-reaktiv oqsil darajasining ko’tarilishini ko’rsatadi. Asoratlar, masalan, o’tkir buyrak shikastlanishi, jigar disfunktsiyasi va ikkilamchi bakterial infektsiyalar keng tarqalgan, va bu guruhda ventilyatsiya yordamiga bo’lgan ehtiyoj yoshlar bilan solishtirganda yuqori.
Xulosa. Keksalar orasida COVID-19ni samarali boshqarish tez tashxis, shaxsiylashtirilgan davolash strategiyalari va asoratlarni diqqat bilan kuzatishni talab qiladi. Ushbu zaif yosh guruhiga xos bo’lgan aniq protokollarni ishlab chiqish uchun qo’shimcha tadqiqotlar zarur.
Mualliflar haqida
Adabiyotlar ro'yxati
Kovalev S.A., Malikov V.E., Effectiveness of pharmacotherapy in normalizing the level of brain natriuretic peptide and activity of the renin-angiotensin-aldosterone system after myocardial revascularization in patients with post-infarction cardiosclerosis, Cardiovascular Therapy and Prevention, 2016, 15, 06, 39-45, 10.15829/1728-8800-2016-6-39-45.
Osipova O.A., Nagibina A.I., Komisov A.A., Pathomorphological mechanisms of myocardial fibrosis regulation in patients with chronic heart failure against the background of ischemic heart disease, Heart Failure, 2019, 17, 05, 357-364, https://www.rmj.ru/articles/kardiologiya/.
Revishvili A.Sh., Golitsyn S.P., Egorov D.F., Russian Clinical Guidelines for the Control of Sudden Cardiac Arrest and Sudden Cardiac Death, Prevention and First Aid, Bulletin of Arrhythmology, 2017, 89, 2-104, https://vestar.elpub.ru/jour/article/view/77.
Uskov V.M., Modeling, Algorithmization, and Forecasting of Outcomes in Transmural Myocardial Infarction with Various Medication Schemes: Author’s Abstract for Medical Sciences Dissertation, Voronezh State Technical University, , 2004, https://www.dissercat.com/content/modelirovanie- algoritmizatsiya-i-prognozirovanie-iskhodov-transmuralnogo-infarkta-miokarda.
Fomin I.V., Chronic Heart Failure in the Russian Federation: What We Know Today and What We Should Do, Russian Cardiological Journal, 2016, 8, 0136, 7-13, 10.15829/1560-4071-2016-8-7-13.
Bouisset F., Gerbaud E., Bataille V., Coste P., Puymirat E., Belle L., Percutaneous Myocardial Revascularization in Late-Presenting Patients with STEMI, Journal of the American College of Cardiology, 2021, 78, 1291-1305, 10.1016/j.jacc.2021.07.039.
Chackerian A.A., Oldham E.R., Murphy E.E., Schmitz J., Pflanz S., Kastelein R.A., IL-1 Receptor Accessory Protein and ST2 Comprise the IL-33 Receptor Complex, Journal of Immunology, 2007, 179, 04, 2551-2555, 10.4049/jimmunol.179.4.2551.
Ciccone M.M., Cortese F., Gesualdo M., Riccardi R., Di Nunzio D., Moncelli M., Iacoviello M., Scicchitano P.A., Novel Cardiac Biomarker: ST2: A Review, Molecules, 2013, 18, 15314-15328, 10.3390/molecules181215314.
Felker G.M., Fiuzat M., Thompson V., Shaw L.K., Neely M.L., Adams K.F., Whellan D.J., Donahue M.P., Ahmad T., Kitzman D.W., Pina I.L., Zannad F., Kraus W.E., O’Connor C.M., Soluble ST2 in Ambulatory Patients with Heart Failure: Association with Functional Capacity and Long-Term Outcomes, Circulation: Heart Failure, 2013, 6, 1172-1179, 10.1161/CIRCHEARTFAILURE.113.000207.
Go A.S., Mozaffarian D., Roger V.L., Heart Disease and Stroke Statistics-2014 Update: A Report from the American Heart Association, Circulation, 2014, 129, 03, 280-292, 10.1161/01.cir.0000441139.02102.80.
Gravning J., Smedsrud M.K., Omland T., Eek C., Skulstad H., Aaberge L., Bendz B., Kjekshus J., Morkrid L., Edvardsen T., Sensitive Troponin Assays and N-Terminal Pro-B-Type Natriuretic Peptide in Acute Coronary Syndrome: Prediction of Significant Coronary Lesions and Long-Term Prognosis, American Heart Journal, 2013, 165, 05, 716-724, 10.1016/j.ahj.2013.02.008.
Mosterd A., Hoes A.W., Clinical Epidemiology of Heart Failure, Heart, 2007, 93, 1137-1146, 10.1161/01.cir.0000441139.02102.80.
Maries L., Manitiu I., Diagnostic and Prognostic Values of B-Type Natriuretic Peptides (BNP) and N-terminal Fragment Brain Natriuretic Peptides (NT-pro-BNP), Cardiovascular Journal of Africa, 2013, 24, 07, 286-289, 10.5830/cvja-2013-055.
Menon V., Pearte C.A., Buller C.E., Steg Ph.G., Forman S.A., White H.D., Lack of Benefit from Percutaneous Intervention of Persistently Occluded Infarct Arteries after the Acute Phase of Myocardial Infarction is Time Independent: Insights from Occluded Artery Trial, European Heart Journal, 2009, 30, 183-191, 10.1093/eurheartj/ehn486.
Nichols M., Townsend N., Scarborough P., Rayner M., Cardiovascular Disease in Europe 2014: Epidemiological Update, European Heart Journal, 2014, 35, 042, 2950-2959, 10.1093/eurheartj/ehu299.
Scho¨mig A., Mehilli J., Antoniucci D., Ndrepepa G., Markwardt C., Di Pede F., Mechanical Reperfusion in Patients with Acute Myocardial Infarction Presenting More Than 12 Hours from Symptom Onset: A Randomized Controlled Trial, JAMA, 2005, 293, 2865-2872, 10.1001/jama.293.23.2865.
Steg P.G., Dabbous O.H., Feldman L.J., Determinants and Prognostic Impact of Heart Failure Complicating Acute Coronary Syndromes: Observations from the Global Registry of Acute Coronary Events (GRACE), Circulation, 2004, 109, 494-499, 10.1161/01.cir.0000109691.16944.da.
Ndrepepa G., Kastrati A., Mehilli J., Antoniucci D., Scho¨mig A., Mechanical Reperfusion and Long-Term Mortality in Patients with Acute Myocardial Infarction Presenting 12 to 48 Hours from Onset of Symptoms, JAMA, 2009, 301, 487-488, 10.1001/jama.2009.32.
Copyright (c) 2024 С.Ж. Муминов, Г.М. Тулабоева, Ю.Ш. Талипова, А.А. Мангосян, Н.М. Абдукадирова, Ж.И. Тоштемиров (Автор)
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