Uyqu arteriyalaridagi beqaror aterosklerotik blyashkalar tasviriy belgilarining zamonaviy yondashuvlari: adabiyotlar sharhi

https://doi.org/10.70626/cardiouz-2025-2-55
TO'LIQ MATN:

Annotatsiya








Uyqu arteriyasi aterosklerozi ishemik insult va boshqa yurak-qon tomir asoratlarining yetakchi sabablaridan biridir. Beqaror aterosklerotik blyashkaning yorilishi o‘tkir miya qon aylanishi buzilishlariga olib kelishi mumkin, shuning uchun o‘z vaqtida tashxis qo‘yish va xavfni baholash nihoyatda muhimdir. Ushbu sharhda blyashka beqarorligining belgilarini aniqlashda qo‘llaniladigan zamonaviy tasvirlash usullari — magnit-rezonans tomografiya (MRT), kompyuter tomografiyasi (KT), pozitron-emission tomografiya (PET) va ultratovush tekshiruvi (UT) — ko‘rib chiqiladi. Har bir usulning diagnostik imkoniyatlari va afzalliklariga, shuningdek, ularning birgalikda qo‘llanilishiga alohida e’tibor qaratiladi, bu esa qon tomir hodisalarini prognozlash aniqligini oshiradi. Tadqiqot natijalari shuni ko‘rsatadiki, gibrid yondashuvlar — masalan, UT + MRT yoki KT + PET — beqaror blyashkalarni aniqlashda 93% gacha aniqlikka erishadi. Tasviriy diagnostika usullari blyashka morfologiyasi, lipid yadrosi, fibroz qopqoq qalinligi, yallig‘lanish va neovaskulyarizatsiya darajasini batafsil baholash imkonini beradi. Elastografiya va sun’iy intellekt yordamida tasvirlarni tahlil qilish kabi ilg‘or texnologiyalar aterosklerozli bemorlarni tashxislash va kuzatishda yangi istiqbollarni ochmoqda. Shunday qilib, kompleks tasvirlash strategiyalarini joriy etish yuqori xavfli insult bemorlarini erta aniqlashga va yurak-qon tomir kasalliklarini oldini olish hamda davolash samaradorligini oshirishga yordam beradi.








Mualliflar haqida

Adabiyotlar ro'yxati

Sorokoumov V, Savello A. Intracranial atherosclerosis: Causes of ischemic stroke, diagnosis, and treatment. Nevrologiya, neiropsikhiatriya, psikhosomatikaю Neurology, Neuropsychiatry, Psychosomatics. 2014;6(2S):50-55. (In Russ.) https://doi.org/10.14412/2074-2711-2014-2S-50-55.

Bos D, Arshi B, van den Bouwhuijsen QJA, Ikram MK, Selwaness M, Vernooij MW, Kavousi M, van der Lugt A. Atherosclerotic Carotid Plaque Composition and Incident Stroke and Coronary Events. J Am Coll Cardiol. 2021 Mar 23;77(11):1426-1435. https://doi.org/10.1016/j.jacc.2021.01.038.

Baradaran H, Gupta A. Extracranial Vascular Disease: Carotid Stenosis and Plaque Imaging. Neuroimaging Clin N Am. 2021 May;31(2):157-166. https://doi.org/10.1016/j.nic.2021.02.002.

Spence JD. Assessment of atherosclerosis: should coronary calcium score and intima-media thickness be replaced by ultrasound measurement of carotid plaque burden and vessel wall volume? Curr Opin Lipidol. 2023 Jun 1;34(3):126-132. https://doi.org/10.1097/MOL.0000000000000880.

Fedak A, Ciuk K, Urbanik A. Ultrasonography of vulnerable atherosclerotic plaque in the carotid arteries: B-mode imaging. J Ultrason. 2020;20(81):e135-e145. https://doi.org/10.15557/JoU.2020.0022.

Ignatyev IM, Gafurov MR, Krivosheeva NV. Criteria for Carotid Atherosclerotic Plaque Instability. Ann Vasc Surg. 2021 Apr;72:340-349. https://doi.org/10.1016/j.avsg.2020.08.145.

Scoutt LM, Gunabushanam G. Carotid Ultrasound. Radiol Clin North Am. 2019 May;57(3):501-518. https://doi.org/10.1016/j.rcl.2019.01.008.

Catalano O, Bendotti G, Aloi TL, Bardile AF, Memmi M, Gambelli P, Zanaboni D, Gualco A, Cattaneo E, Mazza A, Frascaroli M, Eshja E, Bellazzi R, Poggi P, Forni G, La Rovere MT. Evidence of Carotid Atherosclerosis Vulnerability Regression in Real Life From Magnetic Resonance Imaging: Results of the MAGNETIC Prospective Study. J Am Heart Assoc. 2023 Jan 17;12(2):e026469. https://doi.org/10.1161/ JAHA.122.026469.

Benson JC, Saba L, Bathla G, Brinjikji W, Nardi V, Lanzino G. MR Imaging of Carotid Artery Atherosclerosis: Updated Evidence on High-Risk Plaque Features and Emerging Trends. AJNR Am J Neuroradiol. 2023 Aug;44(8):880-888. https://doi.org/10.3174/ajnr.A7921.

Maes L, Versweyveld L, Evans NR, McCabe JJ, Kelly P, Van Laere K, Lemmens R. Novel Targets for Molecular Imaging of Inflammatory Processes of Carotid Atherosclerosis: A Systematic Review. Semin Nucl Med. 2024 Sep;54(5):658-673. https://doi.org/10.1053/j.semnuclmed.2023.10.004.

Gardener H, Caunca MR, Dong C, Cheung YK, Elkind MSV, Sacco RL, Rundek T, Wright CB. Ultrasound Markers of Carotid Atherosclerosis and Cognition: The Northern Manhattan Study. Stroke. 2017 Jul;48(7):1855-1861. https://doi.org/10.1161/STROKEAHA.117.016921.

Piri R, Gerke O, Høilund-Carlsen PF. Molecular imaging of carotid artery atherosclerosis with PET: a systematic review. Eur J Nucl Med Mol Imaging. 2020 Jul;47(8):2016-2025. https://doi.org/10.1007/s002 59-019-04622-y.

Bengtsson A, Nyman E, Gro¨ nlund C, Wester P, Na¨slund U, Fha¨rm E, Norberg M. Multi-view carotid ultrasound is stronger associated with cardiovascular risk factors than presence of plaque or single carotid intima media thickness measurements in subclinical atherosclerosis. Int J Cardiovasc Imaging. 2023 Aug;39(8):1461-1471. https://doi.org/10.1007/s10554-023-02868-0.

Dzaye O, Razavi AC, Dardari ZA, Nasir K, Matsushita K, Mok Y, Santilli F, Cobo AML, Johri AM, Albrecht G, Blaha MJ. Carotid Ultrasound-Based Plaque Score for the Allocation of Aspirin for the Primary Prevention of Cardiovascular Disease Events: The Multi-Ethnic Study of Atherosclerosis and the Atherosclerosis Risk in Communities Study. J Am Heart Assoc. 2024 Jun 18;13(12):e034718. https://doi.org/10.1161/JAHA.123.034718.

Saba L, Nardi V, Cau R, Gupta A, Kamel H, Suri JS, Balestrieri A, Congiu T, Butler APH, Gieseg S, Fanni D, Cerrone G, Sanfilippo R, Puig J, Yang Q, Mannelli L, Faa G, Lanzino G. Carotid Artery Plaque Calcifications: Lessons From Histopathology to Diagnostic Imaging. Stroke. 2022 Jan;53(1):290-297. https://doi.org/10.1161/STROKEAHA.121.035692.

Maggi P, Ricci ED, Muccini C, Galli L, Celesia BM, Ferrara S, Salameh Y, Basile R, Di Filippo G, Taccari F, Tartaglia A, Castagna A. Subclinical atherosclerosis as detected by carotid ultrasound and associations with cardiac and HIV-specific risk factors; the Archi-Prevaleat project. HIV Med. 2023 May;24(5):596-604. https://doi.org/10.1111/hiv.13448.

Goudot G, Sitruk J, Jimenez A, Julia P, Khider L, Alsac JM, El Batti S, Bruneval P, Amemyia K, Pedreira O, Mortelette H, Calvet D, Tanter M, Mirault T, Pernot M, Messas E. Carotid Plaque Vulnerability Assessed by Combined Shear Wave Elastography and Ultrafast Doppler Compared to Histology. Transl Stroke Res. 2022 Feb;13(1):100-111. https://doi.org/10.1007/s12975-021-00920-6.

Roy Cardinal MH, Heusinkveld MHG, Qin Z, Lopata RGP, Naim C, Soulez G, Cloutier G. Carotid Artery Plaque Vulnerability Assessment Using Noninvasive Ultrasound Elastography: Validation With MRI. AJR Am J Roentgenol. 2017 Jul;209(1):142-151. https://doi.org/10.2214/AJR.16.17176.

Davidhi A, Rafailidis V, Destanis E, Prassopoulos P, Foinitsis S. Ultrasound Elastography: another piece in the puzzle of carotid plaque vulnerability? Med Ultrason. 2022 Aug 31;24(3):356-363. https://doi.org/10.11152/mu-3190.

Sˇkoloud´ık D, Kesˇnerova´ P, Voma´cˇka J, Hrba´cˇ T, Netuka D, Forostyak S, Roubec M, Herzig R, Belsˇan T; ANTIQUE Trial Group. Shear-Wave Elastography Enables Identification of Unstable Carotid Plaque. Ultrasound Med Biol. 2021 Jul;47(7):1704-1710. https://doi.org/10.1016/j.ultrasmedbio.2021.03.026.

Sultan SR. The prevalence of extracranial carotid atherosclerosis detected via ultrasound imaging: A single-centre study in Jeddah, Saudi Arabia. Saudi Med J. 2024 Jan;45(1):69-73. https://doi.org/10.15537/smj.2024.45.1.20230503.

Benson JC, Nardi V, Bois MC, Saba L, Brinjikji W, Savastano L, Lanzino G, Lerman A. Correlation between computed tomography angiography and histology of carotid artery atherosclerosis: Can semi- automated imaging software predict a plaque’s composition? Interv Neuroradiol. 2022 Jun;28(3):332-337. https://doi.org/10.1177/15910199211031093.

Haider A, Bengs S, Gebhard C, Fiechter M. Hybrid positron emission tomography and magnetic resonance imaging in carotid atherosclerosis: Not ready for prime time? J Nucl Cardiol. 2022 Dec;29(6):3458-3460. https://doi.org/10.1007/s12350-020-02426-4.

Van der Heiden K, Barrett HE, Meester EJ, van Gaalen K, Krenning BJ, Beekman FJ, de Blois E, de Swart J, Verhagen HJM, van der Lugt A, Norenberg JP, de Jong M, Bernsen MR, Gijsen FJH. SPECT/CT imaging of inflammation and calcification in human carotid atherosclerosis to identify the plaque at risk of rupture. J Nucl Cardiol. 2022 Oct;29(5):2487-2496. https://doi.org/10.1007/s12350-021-02745-0.

Wu G, Zhu C, Wang H, Fu D, Lu X, Cao C, Zhang X, Zhu J, Huang L, Mossa-Basha M, Xia S. Co-existing intracranial and extracranial carotid atherosclerosis predicts large-artery atherosclerosis stroke recurrence: a single-center prospective study utilizing combined head-and-neck vessel wall imaging. Eur Radiol. 2023 Oct;33(10):6970-6980. https://doi.org/10.1007/s00330-023-09654-5.

Faust O, Acharya UR, Sudarshan VK, Tan RS, Yeong CH, Molinari F, Ng KH. Computer aided diagnosis of Coronary Artery Disease, Myocardial Infarction and carotid atherosclerosis using ultrasound images: A review. Phys Med. 2017 Jan;33:1-15. https://doi.org/10.1016/j.ejmp.2016.12.005.

Ko'rishlar soni: 27

Qanday qilib iqtibos keltirish kerak

Uyqu arteriyalaridagi beqaror aterosklerotik blyashkalar tasviriy belgilarining zamonaviy yondashuvlari: adabiyotlar sharhi. (2025). O’ZBEKISTON KARDIOLOGIYASI, 2(3), 235-244. https://doi.org/10.70626/cardiouz-2025-2-55

O‘xshash maqolalar

Shuningdek, ushbu maqola bo‘yicha o‘xshash maqolalarni kengaytirilgan qidirishni boshlash amalga oshirishingiz mumkin.

ISSN 3060-4850 (Print)