Murakkab teri orqali koronar aralashuvda tomir ichi vizualizatsiyasi va fiziologik baholash usullarining roli: sistematik adabiyotlar sharhi
Qabul qilingan: 2026-02-23
Nashr etilgan: 2026-06-29
Annotatsiya
Ushbu sistematik adabiyotlar sharhida murakkab teri orqali koronar aralashuv (TOKA) amaliyotlarida tomir ichi vizualizatsiyasi (IVUS, OKT) va fiziologik baholash usullarining (FFR, iFR) diagnostik va klinik ahamiyati tahlil qilingan. Maqsad. Murakkab koronar zararlanishlarda tomir ichi vizualizatsiyasi va fiziologik baholash usullarining TOKA natijalariga ta’sirini sistematik ravishda baholash. Material va usullar. 2009–2025 yillarda PubMed, Scopus, Web of Science va Google Scholar ma’lumotlar bazalarida chop etilgan 39 ta ilmiy manba, jumladan RENOVATE-COMPLEX-PCI, ULTIMATE, ILUMIEN IV, FAME 1–3, DEFINE-FLAIR va iFR-SWEDEHEART kabi yirik randomizatsiyalashtirilgan klinik tadqiqotlar, meta-tahlillar va xalqaro konsensus hujjatlari tahlil qilingan. Natijalar. Tomir ichi vizualizatsiyasi (IVUS yoki OKT) yo’riqnomasi bilan o’tkazilgan TOKA, an’anaviy angiografiyaga qaraganda 2 yillik MACE darajasini 28% ga kamaytirishi aniqlangan (HR 0,72; 95% CI 0,62–0,85). FFR va iFR yo’riqnomali TOKA strategiyalari o’zaro ekvivalent natijalarni ko’rsatgan. Murakkab TOKA sharoitida intravascular imaging bilan o’tkazilgan amaliy-otlarda birlamchi yakuniy nuqta 7,7% ni, angiografiya guruhida esa 12,3% ni tashkil etgan (HR 0,64; p=0,008). Xulosa. Murakkab koronar zararlanishlarda tomir ichi vizualizatsiyasi va fiziologik baholash usullarini qo’llash klinik natijalarni sezilarli yaxshilaydi va zamonaviy yo’riqnomalarda yuqori darajadagi tavsiya sifatida belgilangan.
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