Gestatsion arterial gipertenziyasi bo‘lgan ayollarni olib borishga oid terapevtik yondashuvlar: kardiolog nuqtayi nazaridan

https://doi.org/10.70626/cardiouz-2025-2-%25x
TO'LIQ MATN:

Annotatsiya








Gipertenziv buzilishlari bo‘lgan homilador ayollarni gestatsion davrning eng erta bosqichlarida olib borish bo‘yicha bilimlarni kengaytirish zarurati bir nechta omillar bilan izohlanadi. Birinchidan, optimal antigipertenziv terapiya sxemasini tanlash vakillik populyatsiyalarida keng ko‘lamli tadqiqotlar o‘tkazish imkoniyatining vaqt cheklanganligi va nafaqat ona, balki bola hayoti uchun ham mas’uliyat mavjudligi sababli cheklangan. Ikkinchidan, amaldagi tavsiyalar asosan arterial bosim darajasidan qat’i nazar, monoterapiyani titrlashdan boshlashni taklif qiladi, bu esa kombinatsiyalangan sxemalarning qo‘llanilishini cheklaydi. Uchinchidan, kardiologik xavflarning o‘ziga xos turlarini aniqlash samarali skrining strategiyasini o‘z vaqtida amalga oshirish bilan cheklangan.






 


Mualliflar haqida

Adabiyotlar ro'yxati

De Backer J., Haugaa K., et al. 2025 ESC Guidelines for the management of cardiovascular disease and pregnancy. European Heart Journal. 2025;00:1-107. https://doi.org/10.1093/eurheartj/ehaf193.

Magee LA et al., NEJM, 2015;372:407–417. https://doi.org/https://doi.org/10.1056/NEJMoa1404595.

Tita ATN et al., NEJM, 2022;386:1781–1792. https://doi.org/10.1056/NEJMoa2201295.

Abalos E., Duley L., Steyn D.W., Henderson-Smart D.J. Antihypertensive drug therapy for mild to moderate hypertension during pregnancy. Cochrane Database of Systematic Reviews. 2018, Issue 10. Art. No.: CD002252. https://doi.org/10.1002/14651858.CD002252.pub4.

Sridharan K., Sequeira R.P. Drugs for treating severe hypertension in pregnancy: a network meta-analysis and trial sequential analysis of randomized clinical trials. Br J Clin Pharmacol. 2018;84(9):1906-1916. https://doi.org/10.1111/bcp.13649.PMID:29974489.

George R., Thomas C., Anna Joy C., Varghese B., Undela K., Adela R. Comparative efficacy and safety of oral nifedipine with other antihypertensive medications in the management of hypertensive disorders of pregnancy: a systematic review and meta-analysis of randomized controlled trials. J Hypertens. 2022;40(10):1876–1886. https://doi.org/10.1097/HJH.0000000000003233.

Yin J., Mei Z., Shi S., Du P., Qin S. Nifedipine or amlodipine? The choice for hypertension during pregnancy: a systematic review and meta-analysis. Arch Gynecol Obstet. 2022; 306(6): 1891–1900. https://doi.org/10.1007/s00404-022-06504-5.

Bajpai D., Popa C., Verma P., Dumanski S., Shah S. Evaluation and Management of Hypertensive Disorders of Pregnancy. Kidney360. 2023;4(10):1512-1525. https://doi.org/10.34067/KID.0000000000000228.

Awaludin A., Rahayu C., Daud N.A.A., Zakiyah N. Antihypertensive Medications for Severe Hypertension in Pregnancy: A Systematic Review and Meta-Analysis. Healthcare (Basel). 2022;10(2):325. https://doi.org/10.3390/healthcare10020325.

Rismiati H., Lee H.-Y. Blood pressure control in hypertensive disorders of pregnancy. Cardiovascular Prevention Pharmacotherapy. 2022;4(3):99-105. https://doi.org/10.36011/cpp.2022.4.e16.

Al Khalaf S., Khashan A.S., Chappell L.C., O’Reilly E´ .J., McCarthy F.P. Role of Antihypertensive Treatment and Blood Pressure Control in the Occurrence of Adverse Pregnancy Outcomes: A Population- Based Study of Linked Electronic Health Records. Hypertension. 2022;79(7):1548-1558. https://doi.org/ 10.1161/HYPERTENSIONAHA.122.18920.

Garcia JE, Mulrenin IR, Nguyen AB, Loop MS, Daubert MA, Urrutia RP, Lee CR. Antihypertensive medication use during pregnancy in a real-world cohort of patients diagnosed with a hypertensive disorder of pregnancy. Frontiers in Cardiovascular Medicine. 2023; 10:1225251. https://doi.org/10.3389/fcvm.20 23.1225251. Available from: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10360165/.

Brown CM, Garovic VD. Drug treatment of hypertension in pregnancy. Drugs. 2014 Mar;74(3):283-96. https://doi.org/10.1007/s40265-014-0187-7. PMID:24554373.

J Vaclavik, Z Ramik, J Jarkovsky, A Zouharova, R Pohlova, J Jirova European Heart Journal, Volume 45, Issue Supplement_1, October 2024, ehae666.2557, https://doi.org/10.1093/eurheartj/ehae666.2557 Published: 28 October 2024.

Duhalde V., Delarue C., Lacroix I., Suarez C., Bourrel R., Montastruc J.L., et al. (2011). Antihypertensive drug prescription pattern before and during pregnancy in France. Pregnancy Hypertens. Int. J. Women’s Cardiovasc. Health 1 (2), 185–189. https://doi.org/10.1016/j.preghy.2011.01.001.

di Pasquo E., Giannubilo S.R., Valentini B., Salvi S., Rullo R., Fruci S., et al. (2024). The “Preeclampsia and Hypertension Target Treatment” study: a multicenter prospective study to evaluate the effectiveness of the antihypertensive therapy based on maternal hemodynamic findings. Am. J. Obstet. Gynecol. MFM 6 (5), 101368. https://doi.org/10.1016/j.ajogmf.2024.101368.

Bortolotto M.R., Francisco R.P.V., and Zugaib M. (2018). Resistant hypertension in pregnancy: how to manage? Curr. Hypertens. Rep. 20 (8), 63. https://doi.org/10.1007/s11906-018-0865-z.

Ashworth D., Battersby C., Bick D., Green M., Hardy P., Leighton L., et al. (2023). A treatment strategy with nifedipine versus labetalol for women with pregnancy hypertension: study protocol for a randomised controlled trial (Giant PANDA). Trials 24 (1), 584. https://doi.org/10.1186/s13063-023-07582-9.

Fitton C.A., Steiner M.F.C., Aucott L., Pell J.P., Mackay D.F., Fleming M., et al. (2017). In-utero exposure to antihypertensive medication and neonatal and child health outcomes: a systematic review. J. Hypertens. 35 (11), 2123–2137. https://doi.org/10.1097/HJH.0000000000001456.

Gestational Hypertension and Preeclampsia (2020). Gestational hypertension and preeclampsia: ACOG practice bulletin, number 222. Obstetrics Gynecol. 135 (6), e237–e260. https://doi.org/10.1097/AOG.00 00000000003891.

Khan K.S., Wojdyla D., Say L., Gu¨lmezoglu A.M., and Van Look P.F. (2006). WHO analysis of causes of maternal death: a systematic review. Lancet 367 (9516), 1066–1074. https://doi.org/10.1016/S0140-6736(06)68397-9.

Hitti J., Sienas L., Walker S., Benedetti T.J., and Easterling T. (2018). Contribution of hypertension to severe maternal morbidity. Am. J. Obstet. Gynecol. 219 (4), e1–e405. https://doi.org/10.1016/j.ajog.2018.07.002.

Scott, G., Gillon T.E., Pels A., von Dadelszen P., and Magee L.A. (2022). Guidelines—similarities and dissimilarities: a systematic review of international clinical practice guidelines for pregnancy hypertension. Am. J. Obstet. Gynecol. 226 (2), S1222–S1236. https://doi.org/10.1016/j.ajog.2020.08.018.

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Gestatsion arterial gipertenziyasi bo‘lgan ayollarni olib borishga oid terapevtik yondashuvlar: kardiolog nuqtayi nazaridan. (2025). O’ZBEKISTON KARDIOLOGIYASI, 2(4), 403-411. https://doi.org/10.70626/cardiouz-2025-2-%x

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