FEATURES OF THE DAILY BLOOD PRESSURE PROFILE FOR DIABETES MELLITUS
Received: 2024-10-10
Published: 2024-12-30
Abstract
Aim of the study: To evaluate the diagnostic significance of ABPM and to identify the features of the daily blood pressure profile (BPAP) in patients with hypertension in combination with type 2 diabetes.
Materials and methods of research: 412 patients with AH I-III degree and type 2 diabetes were analyzed. All patients underwent clinical and instrumental studies. The 24-hour blood pressure profile was assessed using the “Medicom-combi” apparatus (Russia) with the oscillometric method. Statistical analysis was carried out using the SPSS 27.0 application package.
Results of the study: Patients were divided into 2 groups taking into account the presence of diabetes: group 1 consisted of patients with AH and diabetes 2 (n=121), group 2 patients with AH without diabetes 2 (n=291). When analyzing ABPM indicators, it was revealed that hypertensive patients with type 2 diabetes had statistically significant high values of average daily SBP (p = 0.023) and DBP (p = 0.021), average daily SBP (p = 0.046), average daily PBP (p = 0.012 ) compared to hypertensive patients without diabetes. The variability of SBP and DBP between groups did not differ significantly. In patients with hypertension and type 2 diabetes, there was a statistically significant insufficient decrease in SBP at night (p = 0.019). Analysis of dipping status showed that in patients with hypertension and type 2 diabetes, the number of dippers according to SBP was significantly lower compared to patients with hypertension without type 2 diabetes (p = 0.0004), the number of non-dippers and night-pickers was also greater in the group of patients with hypertension and type 2 diabetes, but without statistical significance. The groups did not differ from each other in the number of overdippers.
Conclusions: To identify the characteristics of ABPM, it is advisable for all patients with hypertension and type 2 diabetes to undergo ABPM. Patients with hypertension and type 2 diabetes are characterized by more pronounced disturbances in SPBP, in the form of a lack of adequate reduction in nocturnal blood pressure.
Keywords
List of references
-
Mancia G.; Kreutz R.; Brunstr¨om M.; et al. 2023 ESH Guidelines for the management of arterial hypertension. J. Hypertens. 2023, 41, 1874–2071.
-
Wilson P.W.; Cupples C.F.; Kannel W.B. Is hyperglycemia associated with cardiovascular disease? The Framingham Study. Amer. Heart J. 1991, 121, 586–590.
-
Cooper M. The prevalence of hypertension in patients with diabetes. In: Hypertension and Diabetes; Mogensen C.E., Ed.; Lippincott Williams & Wilkins: London, 2003; pp. 3–9.
-
Parving H.-H. Hypertension and diabetes: the scope of the problem. Blood Pressure 2001, 10 (Suppl. 2), 25–31.
-
Кобалава Ж.Д.; Конради А.О.; Недогода С.В.; и др. Артериальная гипертензия у взрослых. Клинические рекомендации – 2020. Российский кардиологический журнал 2020, 25(3), 3786.
-
Иванова И.В.; Мелехина Е.Н.; Ющук А.М.; Мкртумян И.И.; Тельтевская Е.Ю.; Труш С.В. Анализ показателей офисного и амбулаторного суточного мониторирования артериального давления как предмет особого внимания для оценки эффективности лечения артериальной гипертензии у больных сахарным диабетом 2 типа. Эффективная фармакотерапия 2023, 19(34), 16–22.
-
Карпов Р.С.; Кошельская О.А. Особенности суточного профиля артериального давления при ассоциации сахарного диабета с артериальной гипертонией: связь с длительностью заболевания. Сахарный диабет 2008, 1, 30–33.
-
Медведева М.С.; Мухина Д.Д.; Тарасов А.Н.; Челпанов С.Н.; Елсукова О.С. Диагностическая значимость суточного мониторирования артериального давления при сахарном диабете 2 типа. Academy 2017, 89–92
About the Authors
License
This work is licensed under a Creative Commons Attribution 4.0 International License.
How to Cite
